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(R,S)-Baclofen

GABAB agonist

Product Code: Asc-149

Purity: >99%

  
Pack Size

 

1g
Buy (R,S)-Baclofen from Abcam
Biological Description

Selective GABAB receptor agonist. Antispasmodic.
Useful References

(1995) A physiological role for GABAB receptors and the effects of baclofen in the mammalian central nervous system. Prog Neurobiol. 46:423-62. abstract

(2006) Development of baclofen tolerance in a rat model of chronic spasticity and rigidity. Neurosci Lett. 403:195-200 abstract

(1981) 3H-Baclofen and 3H-GABA bind to bicuculline-insensitive GABAB sites in rat brain. Nature 290:149-52 abstract

Citations

Regulation of hippocampal cannabinoid CB1 receptor actions by adenosine A1 receptors and chronic caffeine administration: implications for the effects of Δ9- … abstract

Chemical Information

(R,S)-4-Amino-3-(4-chlorophenyl)butanoic acid

Asc-149
  • Store at RT
  • MW 213.66
  • Soluble in 1 eq. NaOH to 100 mM
  • C10H12ClNO2
  • 1134-47-0