Home > Receptors & Transporters > Glutamate > Transporters > (S)-3,5-DHPG 

(S)-3,5-DHPG

Selective group I mGlu agonist

Product Code: Asc-007

Purity: >99%

 
Pack Size

 

5mg

10mg

Buy (S)-3,5-DHPG from Abcam
Biological Description

Selective group I mGlu agonist.

Useful References

(2002) (S)-3,5-DHPG: a review.CNS Drug Rev. 8:101 abstract

(2005) Ionotropic and metabotropic glutamate receptor structure and pharmacology. Psychopharmacol. 179:4 abstract

(2005) Behavioral and convulsant effects of the (S) enantiomer of the group I metabotropic glutamate receptor agonist 3,5-DHPG in mice. Neuropharmacology 48:779-87 abstract

Citations

Topolnik et al. (2009) Activity-Dependent Compartmentalized Regulation of Dendritic Ca2+ Signaling in Hippocampal Interneurons. J Neurosci 29(14):4658-4663 abstract

Novel mGluR-and CB1R-Independent Suppression of GABA Release Caused by a Contaminant of the Group I Metabotropic Glutamate Receptor Agonist, … abstract

Increased group I metabotropic glutamate receptor activity in paraventricular nucleus supports elevated sympathetic vasomotor tone in hypertension abstract

Spinal protein kinase M ζ underlies the maintenance mechanism of persistent nociceptive sensitization abstract

Indirect modulation of neuronal excitability and synaptic transmission in the hippocampus by activation of proteinase‐activated receptor‐2 abstract

Excitatory modulation in the cochlear nucleus through group I metabotropic glutamate receptor activation abstract

Functional impact of allosteric agonist activity of selective positive allosteric modulators of metabotropic glutamate receptor subtype 5 in regulating central nervous … abstract

Spinal Sensitization Mechanisms Promoting Pain: Gabaergic Disinhibition and Pkmζ-Mediated Plasticity abstract

Homer 1a gates the induction mechanism for endocannabinoid-mediated synaptic plasticity abstract

Depolarization-induced slow current in cerebellar Purkinje cells does not require metabotropic glutamate receptor 1 abstract

Purine receptor‐mediated endocannabinoid production and retrograde synaptic signalling in the cerebellar cortex abstract

Chemical Information

(S)-3,5-Dihydroxyphenylglycine

Asc-007
  • Desiccate at -20°C
  • MW 183.16
  • Soluble in water to 50 mM
  • C8H9NO4
  • 162870-29-3