2-Chloroadenosine (CADO)

Adenosine agonist

Pack Size

Biological Description Adenosine receptor agonist. Metabolically stable analogue of adenosine. Anticonvulsant effects and neuroprotective in vivo.
Useful References
(2001) International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol Rev. 53:527-52 abstract (1982) Adenosine receptors in rat brain membranes: characterization of high affinity binding of [3H]-2-chloroadenosine. Int J Biochem. 14:399-404. abstract (1997) Effect of intraperitoneal and intrahippocampal (CA1) 2-chloroadenosine in amygdaloid kindled rats. Brain Res. 751:259-64 abstract
Citations
Adenosine A2A receptor induces protein kinase A-dependent functional modulation of human α3β4 nicotinic receptor abstract
Chemical Information 6-Amino-2-chloropurine riboside
	Desiccate at +4°C MW 301.69 Soluble in DMSO to 25 mM C₁₀H₁₂ClN₅O₄ 146-77-0