2,3-Butanedione 2-monoxime (BDM)
Non-selective myosin ATPase inhibitorOther names: BDM / Biacetyl monoxime / Diacetyl monoxime | ||||
Product Code: Asc-616 |
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| Buy 2,3-Butanedione 2-monoxime (BDM) from Abcam | |||
Biological DescriptionNon-selective myosin ATPase inhibitor (Ki = 5 mM at myosin II). Potent Kv2.1 (DRK1) and L-Type Ca2+ channel inhibitor (Ki and IC50 values are 10.7 nM and 5.8 mM respectively). Blood brain barrier permeable. Inhibits muscle contraction. |
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Useful References | |
2,3-butanedione monoxime affects cystic fibrosis transmembrane conductance regulator channel function through phosphorylation-dependent and phosphorylation-independent mechanisms: the role of bilayer material properties. abstract 2,3-Butanedione monoxime (BDM) as a myosin inhibitor. abstract Block of ATP-sensitive K+ channels in isolated mouse pancreatic beta-cells by 2,3-butanedione monoxime. abstract | |
Chemical Information2,3-Butanedione monoxime | |
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