Aminoguanidine hydrochloride

NOS inhibitor

Pack Size

Biological Description Irreversible inhibitor of iNOS, displaying 26-fold selectivity over nNOS. In vitro and in vivo inhibitor of the formation of glycosylation end products associated with diabetes and aging.
Useful References
Moore & Handy (1997) Selective inhibitors of neuronal nitric oxide synthase--is no NOS really good NOS for the nervous system? Trends Pharmacol Sci 18:204-11 abstract Stefanovic-Racic (1995) Comparison of the nitric oxide synthase inhibitors methylarginine and aminoguanidine as prophylactic and therapeutic agents in rat adjuvant arthritis. J Rheumatol 22:1922-8 abstract Nilsson et al (1999) Biological effects of aminoguanidine: an update. Inflamm Res. 48:509-15. abstract
Chemical Information Guanylhydrazine hydrochloride
	Store at RT MW 110.55 Soluble in water to 100 mM CH₆N₄.HCl 1937-19-5