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(±)-Anatoxin A fumarate

Potent nicotinic agonist

Product Code: Asc-013

Purity: >98%

  
Pack Size

 

1mg
Buy (±)-Anatoxin A fumarate from Abcam
Biological Description

Potent nicotinic agonist. Neurotoxic alkaloid produced by the cyanobacterium Anabaena flos-aquae. KI values are 1.25 and 1840 nM for α4β2 and α7 nicotinic receptors in rat brain respectively.
Useful References

(1987) Anatoxin-α a potent ligand for nicotinic cholinergic receptors in rat brain.Eur.J.Pharmacol. 135:457 abstract

(UB-165: a novel nicotinic agonist with subtype selectivity implicates the α4β2* subtype in the modulation of dopamine release from rat striatal synaptosomes. J.Neurosci. 20:2783 abstract

(1992) Behavioural effects of anatoxin, a potent nicotinic agonist, in rats. Neuropharmacol. 31:311 abstract

Chemical Information

(±)-2-Acetyl-9-azabicyclo[4.2.1]non-2-ene fumarate

Asc-013
  • Desiccate at +4°C
  • MW 281.31
  • Soluble in water to 50 mM
  • C10H15NO.C4H4O4
  • 64285-06-9