Anisomycin

Protein synthesis inhibitor

Product Code: Asc-495

Purity: >98%

Pack Size

10mg

50mg

Biological Description

Translational inhibitor of protein synthesis. Highly potent activator of kinase cascades. Potently activates stress-activated protein kinases, p38, JNK MAP and other kinases.

Useful References

Anisomycin activates p38 MAP kinase to induce LTD in mouse primary visual cortex. abstract

The protein synthesis inhibitor anisomycin induces macrophage apoptosis in rabbit atherosclerotic plaques through p38 mitogen-activated protein kinase. abstract

Anisomycin-activated protein kinases p45 and p55 but not mitogen-activated protein kinases ERK-1 and -2 are implicated in the induction of c-fos and c-jun. abstract

Chemical Information

(2R,3S,4S)-2-(4-Methoxybenzyl)-3,4-pyrrolidinediol-3-acetate

Desiccate at +4°C
MW 265.31
Soluble in DMSO to 100 mM and in ethanol to 100 mM
C₁₄H₁₉NO₄
22862-76-6

Additional Information

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