BAPTA-AM
Selective Ca2+ chelator. Analogue of BAPTA.Product Code: Asc-503 |
Purity: >98% |
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| Buy BAPTA-AM from Abcam | |||
Biological DescriptionSelective Ca2+ chelator. Cell permeable analogue of BAPTA. Useful for manipulation of intracellular free Ca2+ levels. Shows varied biological activity. Blocks hKv1.5, Kv11.1 (hERG) and hKv1.3 channels (Ki values are 1.23, 1.30 and 1.45 μM respectively). |
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Useful References | |
The membrane permeable calcium chelator BAPTA-AM directly blocks human ether a-go-go-related gene potassium channels stably expressed in HEK 293 cells. abstract Elevation of resting mitochondrial membrane potential of neural cells by cyclosporin A, BAPTA-AM, and bcl-2. abstract Nonsteroidal Anti-Inflammatory Drug Flufenamic Acid Is a Potent Activator of AMP-Activated Protein Kinase. abstract | |
Chemical Information1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl ester) | |
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