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Voltage gated sodium channel blocker

Product Code: Asc-5835

Purity: >99%

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Biological Description

Voltage gated sodium channel blocker. Reversibly stabilizes the neuronal membrane. Inhibits depolarization and prevents neuronal transmission. Shows surface anesthetic effects in vivo.

Useful References

Inhibition of sensory neuronal TRPs contributes to anti-nociception by butamben. abstract

Membrane permeable local anesthetics modulate Na(V)1.5 mechanosensitivity. abstract

Locating the route of entry and binding sites of benzocaine and phenytoin in a bacterial voltage gated sodium channel. abstract

Chemical Information

Ethyl 4-aminobenzoate

  • Desiccate at -20°C
  • MW 165.19
  • Soluble in ethanol to 100 mM and in DMSO to 100 mM
  • C9H11NO2
  • 94-09-7