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Chemistry Lab 360

Low-Cost Custom Synthesis Services

Our synthetic chemistry skills and experience allow us to offer a wide variety of services at an affordable price and tailored to meet your needs.

Experience
Communication
Facilities
Low-Cost
Customers
A typical project
Endorsements
Case Studies

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Experience

Smiling lady

Utilising our teams of experienced and highly qualified chemists we are able to undertake the most challenging of synthetic chemistry projects.

We have years of experience in many areas of chemistry, e.g. amino acids, peptides, nucleic acids, steroids, radiochemical precursors, stable labelled compounds, fluorescent labelling.

During these projects we are able to employ a variety of specialised techniques in order to efficiently achieve the custom synthesis target. For example, these include heterocyclic chemistry, hydrogenation, organometallic chemistry, chiral chemistry, low-temperature chemistry, high pressure chemistry, microwave chemistry, dissolving metal chemistry, chiral salt resolution, chromatography, ion exchange.

Scale is not an issue. We can manufacture quantities from mg to a kg and develop methods suitably optimised for scale-up.

The applications of our custom synthesis products have been diverse, including synthesis of receptor ligands, neurotransmitters, signalling tools, hormones etc. In addition we make intermediates, analogues, impurities and scaffolds to help customers develop their own chemical targets.

Communication

Test tubes

High quality, clear and confidential communication is the essence of exceptional custom synthesis service. During a synthesis you will receive regular and comprehensive reports according to your requirements. You will be assigned a key point of contact for the duration of your project and we are happy to report by any media (e.g. conference call, phone, email). In addition, at the end of a project we will supply a high quality data or information pack as agreed at the outset of any chemical synthesis.

Facilities

Our high-tech, purpose designed production facility enables us to offer the best possible custom synthesis service to our customers. Each chemist is provided with a spacious workplace and equipped with all of the tools necessary to work safely and efficiently.

Low-Cost, affordable chemistry services

As researchers and life scientists ourselves, we passionately believe in furthering research - so we strive to make our services as affordable as possible. Our chemists have decades of synthetic chemistry exerience. We never cut corners, or compromise on quality. We employ innovative manufacturing processes, we keep our costs as low as possible and our margins are modest - enabling us to pass huge cost savings onto our customers.

Customers

We have undertaken a wide variety of synthetic chemistry projects over the last 5 years and have built up strong relationships with customers worldwide. Our custom synthesis client list includes:

• Pharmaceutical & biotechnology companies
• Academic researchers
• Life science reagent companies

References are available on request.

A typical custom synthesis project - what can you expect?

Flow chart
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Endorsements

Bearded Man

“The project couldn’t have gone more smoothly. They kept us in touch with the chemistry progress and delivered exactly what we needed, when we needed it.”
European biotechnology company

“A very professional, confident and friendly service – and at prices that put their competitors to shame!”
US pharmaceutical company

“These guys really know what they are talking about. We had reached an impasse and they made the suggestion that turned our project around. Great work!”
European technology company

“We needed a quick turnaround and Ascent Scientific delivered without cutting corners.”
UK biotechnology company

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Synthetic Chemistry Case Studies

Biosensor in clinical development

Recruited to provide chemical expertise for the development of a sensitive chemical biosensor we successfully produced a target that was incorporated into our customer’s product.The product is currently being tested for clinical use.
European biotechnology company

Stable labelled drug

Working closely with a global pharmaceutical company we synthesised a hetero-isotopically labelled drug molecule for use in ADME studies.
Multinational pharmaceutical company

Membrane impermeable channel blocker

Blue Gloves

Modifying a standard ion channel modulator we manufactured a membrane impermeable tool for use in electrophysiological research.
US academic research group

Reagent Building blocks

We manufactured a broad range of complex chemical products used for a variety of research applications, including screening of potential drug candidates.
Multinational biotechnology company

Neuro-active Peptides

Acting as the chemical arm for a small biotechnology start-up we worked closely with the customer and successfully developed a range of neuroactive dipeptides targeting a neurodegenerative disorder.
UK based biotechnology company

Fluorescently labelled tools

Developed a range of fluorescently labelled inhibitors for use in protein kinase assays.
European biotechnology company

Bioavailable GPCR agonist

We undertook a complex project in method and process development to synthesise bulk quantities of a novel GPCR agonist. Working against a tight fixed deadline we subsequently modified the target to increase its bioavailability. The product is currently in pre-clinical development.
European biotechnology company

Ionic liquids

Successfully manufactured a range of ionic liquids for incorporation into our customer’s new invention.
European Technology company

Modified Polysaccharide

Developed a structurally modified polysaccharide to provide a product with our customers required specifications.
European building technology company

ADME products

Developed a range of closely related standards for use in the analysis of drug impurities and metabolites.
European contract research company

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Our Customers Say…

"… the timing was perfect. I would like to compliment you on the documentation that you provided… We feel very confident in the purity of our compound."

Dr Francine C. Acher Director of Research, CNRS
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Water-soluble glutamate ligands available… water-soluble ligand droplet
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