Cyclopiazonic acid from Penicillium grisefulvum
Ca2+-ATPase inhibitorOther names: α-Cyclopiazonic acid | |||||
Product Code: Asc-300 |
Purity: >99% |
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Biological DescriptionCell-permeable, reversible inhibitor of sarcoplasmic reticulum Ca2+-ATPase. |
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Useful References | |
(1997) On the inhibition mechanism of sarcoplasmic or endoplasmic reticulum Ca2+-ATPases by cyclopiazonic acid. J Biol Chem. 272:2794-800 abstract (1998) Cyclopiazonic acid effect on Ca2+-dependent conformational states of the sarcoplasmic reticulum ATPase. Implication for the enzyme turnover. Biochemistry. 37:4266-74 abstract (2009) Cyclopiazonic Acid Is Complexed to a Divalent Metal Ion When Bound to the Sarcoplasmic Reticulum Ca2+-ATPase. J Biol Chem. 284:13513-8. abstract | |
Citations | |
Neuronal Fc-gamma receptor I mediated excitatory effects of IgG immune complex on rat dorsal root ganglion neurons abstract | |
Chemical Information(6aR,11aS,11bR)-10-acetyl-2,6,6a,7,11a,11b-hexahydro-11-hydroxy-7,7-dimethyl-9H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one | |
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