DR2313 (PARP Inhibitor XI)
Potent, brain-penetrant and water-soluble PARP inhibitorOther names: PARP Inhibitor XI | ||||||
Product Code: Asc-368 |
Purity: >99% |
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| Buy DR2313 (PARP Inhibitor XI) from Abcam | |||||
Biological DescriptionPotent, brain-penetrant, and water-soluble poly(ADP-ribose) polymerase (PARP) inhibitor. IC50 values are 0.20 and 0.24 µM for PARP-1 and PARP-2 respectively. Neuroprotective in vitro and in vivo. |
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Useful References | |
A newly synthesized poly(ADP-ribose) polymerase inhibitor, DR2313 [2-methyl-3,5,7,8-tetrahydrothiopyrano[4,3-d]-pyrimidine-4-one]: pharmacological profiles, neuroprotective effects, and therapeutic time window in cerebral ischemia in rats. abstract | |
Chemical Information1,5,7,8-Tetrahydro-2-methyl-4H-thiopyrano[4,3-d]pyrimidin-4-one | |
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