Genistein

Protein tyrosine kinase inhibitor. Anticancer agent.

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Biological Description Phytoestrogen found in soy beans. Anticancer agent. Inihibits tyrosine protein kinase and DNA topoisomerase as well as possessing antioxidant and cell cycle inhibitor activity.
Useful References
Dixon et al (2002) Genistein. Phytochemistry. 60:205-11. abstract Sarkar et al (2002) Mechanisms of cancer chemoprevention by soy isoflavone genistein. Cancer Metastasis Rev. 21:265-80 abstract Akiyama et al (1987) Genistein, a specific inhibitor of tyrosine-specific protein kinases. 262:5592-5 abstract
Chemical Information 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one
	Desiccate at -20°C MW 270.24 Soluble in DMSO to 100 mM C₁₅H₁₀O₅ 446-72-0