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LY 367385 sodium salt

mGlu1a antagonist. Only available in: mGlu antagonists: Low-Cost Kit (Asc-322).

Product Code: Asc-418

Purity: >99%

  
Pack Size

 
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Biological Description

Potent, selective mGlu1a antagonist. Neuroprotective and anticonvulsant in vivo. Only available in: mGlu antagonists: Low-Cost Kit (Asc-322).
Useful References

Neuroprotective activity of the potent and selective mGlu1a metabotropic glutamate receptor antagonist, (+)-2-methyl-4 carboxyphenylglycine (LY367385): comparison with LY357366, a broader spectrum antagonist with equal affinity for mGlu1a and mGlu5 receptors. abstract

Anticonvulsant actions of LY 367385 ((+)-2-methyl-4-carboxyphenylglycine) and AIDA ((RS)-1-aminoindan-1,5-dicarboxylic acid). abstract

Chemical Information

(S)-(+)-α-Amino-4-carboxy-2-methylbenzeneacetic acid sodium salt

Asc-418
  • Desiccate at RT
  • MW 231.18
  • Soluble in water to 100 mM
  • C10H10NNaO4
  • 198419-91-9 (free acid)
Additional Information

Sold under license from Eli Lilly and company