N6-Cyclohexyladenosine
Selective A1 receptor agonistOther names: CHA | |||||
Product Code: Asc-472 |
Purity: >98% |
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| Buy N6-Cyclohexyladenosine from Abcam | ||||
Biological DescriptionSelective A1 receptor agonist (EC50 = 8.2 nM). Adenosine analogue; exerts anticonvulsant effects and protects against neuronal death. |
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Useful References | |
Anticonvulsant effects of N6-cyclohexyladenosine microinjected into the CA1 region of the hippocampus on entorhinal cortex-kindled seizures in rats. abstract Adenosine A1 receptors mediate the presynaptic inhibition of calcitonin gene-related peptide release by adenosine in the rat spinal cord. abstract Cyclohexyl adenosine protects against neuronal death following ischemia in the CA1 region of gerbil hippocampus. abstract | |
Chemical Information(2R,3S,4R,5R)-2-[6-(Cyclohexylamino)-9H-purin-9-yl]-tetrahydro-5-(hydroxymethyl)furan-3,4-diol | |
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