Home > NG-Monomethyl-L-arginine, monoacetate salt (L-NMMA) 

NG-Monomethyl-L-arginine, monoacetate salt (L-NMMA)

NOS inhibitor

Other names: L-NMMA

Product Code: Asc-137

Purity: >99%

 
Pack Size

 

10mg

50mg

Buy NG-Monomethyl-L-arginine, monoacetate salt (L-NMMA) from Abcam
Biological Description

Cell permeable competitive NOS inhibitor. (Ki values are = 700 nM, 3.9 µM and 650 nM for eNOS, iNOS and nNOS respectively).

Useful References

Rees et al (1999) A specific inhibitor of nitric oxide formation from L-arginine attenuates endothelium-dependent relaxation. Br J Pharmacol 96:418-24 abstract

Cardounel et al (2007) Evidence for the pathophysiological role of endogenous methylarginines in regulation of endothelial NO production and vascular function. J Biol Chem. 282(2):879-87. abstract

Maggie et al (1991) Effect of NG-monomethyl L-arginine (L-NMMA) and NG-nitro L-arginine (L-NOARG) on non-adrenergic non-cholinergic relaxation in the circular muscle of the human ileum. Br J Pharmacol. 103:1970-2 abstract

Chemical Information

NG-Methyl-L-arginine acetate salt

Asc-137
  • Desiccate at RT
  • MW 248.28
  • Soluble in water to 50 mM
  • C7H16N4O2.CH3CO2H
  • 53308-83-1