NKH 477 (Colforsin daropate)
Water-soluble analogue of forskolin (Asc-058), an adenylyl cyclase activatorOther names: Colforsin daropate hydrochloride | |||||
Product Code: Asc-190 |
Purity: >98% |
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Biological DescriptionWater-soluble adenylyl cyclase activator |
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Useful References | |
Hosono et al (1992) Cardiovascular and adenylate cyclase stimulant properties of NKH477, a novel water-soluble forskolin derivative. J Cardiovasc Pharmacol. 19:625-34 abstract Morinobu et al (1999) Stimulation of adenylyl cyclase and induction of brain-derived neurotrophic factor and TrkB mRNA by NKH477, a novel and potent forskolin derivative. J Neurochem. 72:2198-205 abstract Satake et al (1998) Relaxant effects of NKH477, a new water-soluble forskolin derivative, on guinea-pig tracheal smooth muscle: the role of Ca2+-activated K+ channels. Br J Pharmacol. 123:753-61. abstract | |
Chemical InformationN,N-Dimethyl-(3R,4aR,5S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl ester β-alanine hydrochloride | |
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