Pramipexole dihydrochloride
Dopamine D2-like receptor agonist. D3-preferring.Product Code: Asc-569 |
Purity: >99% |
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Biological DescriptionDopamine D2-like receptor agonist showing some selectivity for D3 (Ki values are 3.9, 3.3, 0.5 and 3.9 nM for D2L, D2S, D3 and D4 receptors respectively). Potent anti-oxidant. Displays anti-depressant and anti-Parkinsonian effects. |
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Useful References | |
Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. II. Agonist and antagonist properties at subtypes of dopamine D(2)-like receptor and alpha(1)/alpha(2)-adrenoceptor. abstract Both the antioxidant and D3 agonist actions of pramipexole mediate its neuroprotective actions in mesencephalic cultures. abstract Pramipexole binding and activation of cloned and expressed dopamine D2, D3 and D4 receptors. abstract | |
Chemical Information(S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydrochloride | |
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