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Procaine hydrochloride

Na+ channel blocker. DNA methylation inhibitor.

Product Code: Asc-865

Purity: >99%

 
Pack Size

 

250mg

Buy Procaine hydrochloride from Abcam
Biological Description

Na+ channel blocker (IC50 = 60-200 μM). Local anaesthetic properties in vivo. Crosses the blood-brain barrier. Inhibits DNA methylation.

Also available in simple stock solutions (Asc-6726) - add 1 ml of water to get an exact, ready-to-use concentration.

Useful References

Inhibition of synaptosomal veratridine-induced sodium influx by antidepressants and neuroleptics used in chronic pain. abstract

Relationship between the passage of local anaesthetics across the blood-brain barrier and their effects on the central nervous system. abstract

Procaine inhibits the proliferation and DNA methylation in human hepatoma cells. abstract

Chemical Information

4-Aminobenzoic acid 2-diethylaminoethyl ester hydrochloride

Asc-865
  • Store at RT
  • MW 236.31
  • Soluble in water to 100 mM
  • C13H20N2O2.HCl
  • 51-05-8