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(R,S)-Sulpiride

D2-like dopamine receptor antagonist

Product Code: Asc-578

Purity: >99%

  
Pack Size

 

100mg
Buy (R,S)-Sulpiride from Abcam
Biological Description

D2-like dopamine receptor antagonist. Shows anti-psychotic activity. Active enantiomer (S)-sulpiride (Asc-579) also available.
Useful References

Hypotensive and regional hemodynamic effects of the dopamine receptor agonist SK & F 85174 in the anesthetized rat. abstract

Dopamine D4 receptors bind inactive (+)-aporphines, suggesting neuroleptic role. Sulpiride not stereoselective. abstract

Dopamine receptor pharmacology. abstract

Citations

Cellular mechanisms underlying burst firing in substantia nigra dopamine neurons abstract

Chemical Information

(R,S)-(±)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide

Asc-578
  • Store at +4°C
  • MW 341.42
  • Soluble in DMSO to 100 mM and in 1 eq. HCl to 50 mM
  • C15H23N3O4S
  • 15676-16-1