Ro 31-8220 mesylate (Bisindolylmaleimide IX)
Protein kinase inhibitorOther names: Bisindolylmaleimide IX | ||||||
Product Code: Asc-374 |
Purity: >98% |
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| Buy Ro 31-8220 mesylate (Bisindolylmaleimide IX) from Abcam | |||||
Biological DescriptionWidely used as a cell permeable, reversible, competitive protein kinase C inhibitor. Also potently inhibits wide range of kinases inlcuding RSK1, RSK2, PRK2, PKCα, PKD1, MSK1, GSK3β, CDK2-cyclin A and PIM3, as well as PKCα. |
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Useful References | |
The selectivity of protein kinase inhibitors: a further update. abstract RO 31-8220 and RO 31-7549 show improved selectivity for protein kinase C over staurosporine in macrophages. abstract Inhibitors of protein kinase C. 2. Substituted bisindolylmaleimides with improved potency and selectivity. abstract | |
Chemical Information3-[1-[3-(Amidinothio)propyl]-3-indolyl]-4-(1-methyl-3-indolyl)-1H-pyrrole-2,5-dione methanesulfonate | |
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