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Ropivacaine hydrochloride

Reversible sodium ion influx inhibitor. Long-acting amide local anaesthetic agent.

Product Code: Asc-5733

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Biological Description

Reversible sodium ion influx inhibitor. Long-acting amide local anesthetic agent. Blocks impulse conduction in nerve fibers. Less lipophilic than bupivacaine (Asc-2490, Asc-3182) so shows more sensory nerve selectivity. Shows anesthetic effects in vivo.

Useful References

Nanoanesthesia: a novel, intravenous approach to ankle block in the rat by magnet-directed concentration of ropivacaine-associated nanoparticles. abstract

Different effects of local anesthetics on extracellular signal-regulated kinase phosphorylation in rat dorsal horn neurons. abstract

Effects of various antiepileptics used to alleviate neuropathic pain on compound action potential in frog sciatic nerves: comparison with those of local anesthetics. abstract

Chemical Information

(2S)-N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamide hydrochloride

  • Desiccate at -20°C
  • MW 310.86
  • Soluble in water to 100 mM and in DMSO to 100 mM
  • C17H26N2O.HCl
  • 132112-35-7