(S)-(+)-Rolipram
PDE4 inhibitor; less active enantiomerProduct Code: Asc-030 |
Purity: >99% |
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| Buy (S)-(+)-Rolipram from Abcam | ||||
Biological DescriptionPDE4 inhibitor (IC50 = 0.58 μM). Less active enantiomer. |
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Useful References | |
Schneider et al (1986) Stereospecific binding of the antidepressant rolipram to brain protein structures. Eur.J.Pharmacol. 127:105 abstract Souness and Scott (1993) Stereospecificity of rolipram actions on eosinophil cyclic AMP-specific phosphodiesterase. Biochem.J. 291:389 abstract Wachtel (1983) Neurotropic effects of the optical isomers of the selective adenosine cyclic 3',5'-monophosphate phosphodiesterase inhibitor rolipram in rats in-vivo. J Pharm Pharmacol. 35:440 abstract | |
Chemical Information(S)-4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one | |
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