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Simvastatin

HMG-CoA reductase inhibitor

Product Code: Asc-505

Purity: >99%

 
Pack Size

 

50mg

250mg

Buy Simvastatin from Abcam
Biological Description

HMG-CoA reductase inhibitor. Hypolipidemic, decreasing low denisty lipoprotein (LDL) levels. Implicated in a multitude of biological functions, demonstrating anti-cancer and anti-inflammatory properties.

Useful References

Simvastatin impairs murine melanoma growth. abstract

Simvastatin inhibits growth via apoptosis and the induction of cell cycle arrest in human melanoma cells. abstract

Effect of simvastatin treatment on rat livers subjected to ischemia/reperfusion. abstract

Chemical Information

(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl-2,2-dimethyl butanoate

Asc-505
  • Desiccate at -20°C
  • MW 418.57
  • Soluble in DMSO to 50 mM and in ethanol to 50 mM
  • C25H38O5
  • 79902-63-9