Sodium orthovanadate (for Decavanadate solution)
Broad spectrum inhibitor of tyrosine phosphatasesProduct Code: Asc-386 |
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| Buy Sodium orthovanadate (for Decavanadate solution) from Abcam | ||||
Biological DescriptionBroad spectrum inhibitor of protein tyrosine phosphatases. Also inhibits ATPases. Inhibits apoptosis. Chemical precursor to decavanadate, which is formed at acidic pH; inhibits inositol 1,4,5-trisphosphate (IP3)-induced Ca2+ release from endocrine cells and blocks IP3 binding. |
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Useful References | |
Aureliano et al (2009) Decavanadate: a journey in a search of a role. Dalton Trans. 42:9093-100. abstract Krstic et al (2009) Influence of decavanadate on rat synaptic plasma membrane ATPases activity. Gen Physiol Biophys. 28:302-8 abstract Morita et al (2010) Sodium orthovanadate inhibits p53-mediated apoptosis. Cancer Res. 70:257-65 abstract | |
Chemical InformationSodium orthovanadate | |
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