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Spermidine hydrochloride

Endogenous polyamine. nNOS inhibitor.

Product Code: Asc-057

Purity: >99%

 
Pack Size

 

100mg

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Biological Description

Endogenous polyamine, that binds to the polyamine modulatory site of the NMDA receptor. Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins.

Useful References

(1994) Polyamines inhibit nitric oxide synthase in rat cerebellum. Neurosci. Lett. 175:41-45. abstract

(1997) Purification of human Rad51 protein by selective spermidine precipitation. Mutat. Res. 384: 65-72 abstract

(1994) Sensitivity of the N-methyl-D-aspartate receptor to polyamines is controlled by NR2 subunits. Mol Pharmacol. 45:803-9. abstract

Chemical Information

N-(3-Aminopropyl)butane-1,4-diamine trihydrochloride

Asc-057
  • Desiccate at +4°C
  • MW 254.63
  • Soluble in water to 100 mM
  • C7H19N3.3HCl
  • 334-50-9