Staurosporine
Protein kinase inhibitorProduct Code: Asc-056 |
Purity: >98% |
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Biological DescriptionPotent, cell permeable, broad spectrum inhibitor of protein kinases. Kinases inhibited include: protein kinase C (IC50 = 3 nM), cAMP-dependent protein kinase (IC50 = 8 nM), and p60v-src (IC50 = 6 nM). |
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Useful References | |
Gadbois et al (1992) Staurosporine is a potent inhibitor of p34cdc2 and p34cdc2-like kinases Biochem.Biophys.Res.Comm. 184: 80-5 abstract Ruegg and Burgess (1989) Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases. Trends in Pharmacol.Sci. 10:218-220 abstract | |
Chemical Information[9S-(9α,10β,11β,13α)]-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3,2,1-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one | |
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