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TMCB

Selective CK2 inhibitor

Product Code: Asc-289

Purity: >98%

 
Pack Size

 

10mg

50mg

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Biological Description

CK2 inhibitor (Ki = 0.25 μM), more selective than DMAT. Unlike DMAT, TMCB displays selectivity over PIM1, HIPK2 and DYRK1a (Ki values are 8.65, 15.25 and 11.90 μM respectively) and a more favourable selectivity profile over a range of other kinases.

Useful References

Pagona et al (2008) The selectivity of inhibitors of protein kinase CK2: an update. Biochem J. 415:353-65 abstract

Chemical Information

2-(4,5,6,7-Tetrabromo-2-(dimethylamino)-1H-benzo[d]imidazol-1-yl)acetic acid

Asc-289
  • Store at RT
  • MW 534.82
  • Soluble in DMSO
  • C11H9Br4N3O2
  • 905105-89-7