Vecuronium bromide

Competitive nicotinic acetylcholine receptor (nAChR) antagonist

Pack Size

Biological Description Competitive nicotinic acetylcholine receptor (nAChR) antagonist (IC₅₀ = 9.9 nM). Muscle relaxant. Inhibits neural response to hypoxia.
Useful References
Roles of amino acids and subunits in determining the inhibition of nicotinic acetylcholine receptors by competitive antagonists. abstract Vecuronium directly inhibits hypoxic neurotransmission of the rat carotid body. abstract Site selectivity of competitive antagonists for the mouse adult muscle nicotinic acetylcholine receptor. abstract
Chemical Information 1-[(2β,3α,5α,16β,17β)-3,17-Bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium bromide
	Desiccate at RT MW 637.74 Soluble in DMSO to 100 mM, in ethanol to 100 mM and in water to 25 mM C₃₄H₅₇BrN₂O₄ 50700-72-6