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Verapamil hydrochloride

L-type Ca2+ channel blocker

Product Code: Asc-140

Purity: >99%

 
Pack Size

 

1g

Buy Verapamil hydrochloride from Abcam
Biological Description

L-type Ca2+ channel blocker. Antiarrhythmic in vivo.

Useful References

(1980) Comparative pharmacology of calcium antagonists: nifedipine, verapamil and diltiazem. Am J Cardiol. 46:1047-58 abstract

(1997) Kinetics and state-dependent effects of verapamil on cardiac L-type calcium channels. Naunyn Schmiedebergs Arch Pharmacol. 355:79-86 abstract

(2007) Chronic verapamil treatment remodels ICa,L in mouse ventricle. Am J Physiol Heart Circ Physiol. 292:H1906-16 abstract

Citations

Phosphatidylinositol 3, 5-bisphosphate increases intracellular free Ca2+ in arterial smooth muscle cells and elicits vasocontraction abstract

Chemical Information

5-[N-(3,4-Dimethoxyphenylethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile hydrochloride

Asc-140
  • Store at RT
  • MW 491.06
  • Soluble in water to 50 mM
  • C27H38N2O4.HCl
  • 152-11-4