Z-LE(OMe)VD(OMe)-FMK
Cell permeable derivative of caspase-4 inhibitor Z-LEVD-FMKOther names: Z-LEVD-FMK (cell permeable) | |||||
Product Code: Asc-489 |
Purity: >90% |
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| Buy Z-LE(OMe)VD(OMe)-FMK from Abcam | ||||
Biological DescriptionMethylated, cell permeable derivative of the caspase-4 inhibitor Z-Leu-Glu-Val-Asp-FMK (Z-LEVD-FMK). Once in the cell, endogenous esterase activity hydrolyzes the methyl groups to form the biologically active form. Therefore, when using with isolated, purified or recombinant caspase enzymes, pre-treatment with an esterase is required. |
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Useful References | |
Caspases: killer proteases. abstract Dual involvement of caspase-4 in inflammatory and ER stress-induced apoptotic responses in human retinal pigment epithelial cells. abstract | |
Chemical InformationN-Benzyloxycarbonyl-Leu-Glu(OMe)-Val-Asp(OMe)-fluoromethylketone | |
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