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Z-VAD-FMK

Irreversible general caspase inhibitor

Product Code: Asc-382

Purity: >98%

 
Pack Size

 

1mg

5mg

Buy Z-VAD-FMK from Abcam
Biological Description

An irreversible general caspase inhibitor, useful for non-cellular in vitro  studies involving isolated, purified or recombinant caspase enzymes. Unlike Z-VAD (OMe)-FMK (Asc-487), pretreatment with an esterase is not required.

Useful References

Caspase inhibitors promote alternative cell death pathways. abstract

Inhibition of human caspases by peptide-based and macromolecular inhibitors. abstract

Caspase inhibitors. abstract

Chemical Information

N-Benzyloxycarbonyl-Val-Ala-Asp(O-Me)-fluoromethyl ketone

Asc-382
  • Desiccate at -20°C
  • MW 453.46
  • Soluble in DMSO to 20 mM
  • C21H28FN3O7