ZD7288

Other names: ICI D7288

Product Code: Asc-102

Purity: >98%

(1993) Inhibitory actions of ZENECA ZD7288 on whole cell hyperpolarization activated inward current (If) in guinea-pig dissociated sinoatrial node cells. Br.J.Pharmacol. 110:343 abstract

(2006) The H current blocker ZD7288 decreases epileptiform hyperexcitability in the rat neocortex by depressing synaptic transmission. Neuropharmacology 51:681-91 abstract

(1995) Mechanism of block by ZD7288 of the hyperpolarization-activated inward rectifying current in guinea-pig substantia nigra neurons in vitro. J.Neurophysiol. 74:2366 abstract

Loss of dendritic HCN1 subunits enhances cortical excitability and epileptogenesis abstract

ClC-2 voltage-gated channels constitute part of the background conductance and assist chloride extrusion abstract

Developmental mechanisms for suppressing the effects of delayed release at the endbulb of held abstract

Deletion of the hyperpolarization-activated cyclic nucleotide-gated channel auxiliary subunit TRIP8b impairs hippocampal Ih localization and function and promotes … abstract

Lidocaine blocks the hyperpolarization-activated mixed cation current, Ih, in rat thalamocortical neurons abstract

Funktionelle und molekulare Charakterisierung von hyperpolarisations-aktivierten Kationenströmen im humanen epileptogenen Neokortex abstract

Tuning of synaptic integration in the medial entorhinal cortex to the organization of grid cell firing fields abstract

Differential effects of Na+–K+ ATPase blockade on cortical layer V neurons abstract

Muscarinic Depolarization of Layer II Neurons of the Parasubiculum abstract

Upregulation of inward rectifier K+ (Kir2) channels in dentate gyrus granule cells in temporal lobe epilepsy abstract

• Desiccate at +4°C
• MW 292.81
• Soluble in water to 100 mM
• C₁₅H₂₁ClN₄
• 133059-99-1