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Home > Glutamate > mGlu > Group I > LY 367385

LY 367385      mGlu1a antagonist

Product Code: Asc-067

Purity: >99%

  
         
Biological Description

Potent, selective mGlu1a antagonist. Neuroprotective and anticonvulsant in vivo.
Useful References

Bruno et al (1999) Neuroprotective activity of the potent and selective mGlu1a metabotropic glutamate receptor antagonist, (+)-2-methyl-4 carboxyphenylglycine (LY367385): comparison with LY357366, a broader spectrum antagonist with equal affinity for mGlu abstract

Chapman et al (1999) Anticonvulsant actions of LY 367385 ((+)-2-methyl-4-carboxyphenylglycine) and AIDA ((RS)-1-aminoindan-1,5-dicarboxylic acid). Eur J Pharmacol. 368:17-24 abstract



Chemical Information

(S)-(+)-&alpha-Amino-4-carboxy-2-methylbenzeneacetic acid

Asc-067
  • Desiccate at RT
  • MW 209.20
  • Soluble to 100 mM in 110mM NaOH
  • C10H11NO4
  • 198419-91-9
COA
MSDS
Additional Information

*Sold under license from Eli Lilly and company

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