Philanthotoxin-7,4 GluA1/GluA2 (formerly GluR1/2) inhibitor

Biological Description A subtype-selective, use-dependent inhibitor of native AMPA receptors. Inhibits GluA1/A2 (formerly GluR1/2), with little activity at GluA2/A3 (formerly GluR2/3)
Useful References Nilsen et al (2007) A subtype-selective, use-dependent inhibitor of native AMPA receptors. J Am Chem Soc. 129:4902-3 abstract
Chemical Information (S)-N-[7-[(4-Aminobutyl)amino]heptyl]-4-hydroxy-&alpha-[(1-oxobutyl)amino]benzenepropanamide dihydrochloride
	Desiccate at RT MW 507.54 Soluble to 100 mM in water and to 100 mM in DMSO C₂₄H₄₂N₄O₃.2HCl 401601-12-5