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Novel, caged nicotine compound, uncaged by visible light

Product Code: Asc-450

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Biological Description

Novel, caged ruthenium-bipyridine based nicotine compound. Releases nicotine upon irradiation with biologically harmless blue and green light. Exhibits extremely fast uncaging kinetics, high quantum yield in visible region of the spectrum and high water solubility. Active in biological systems, induces depolarisation and subsequent action potentials in neurons in vivo.

Useful References

A caged nicotine with nanosecond range kinetics and visible light sensitivity. abstract

Chemical Information

Bis(2,2'-bipyridine-N,N')bis(S-nicotine-N1) ruthenium(2+) dichloride complex

  • Desiccate at -20°C
  • MW 808.81
  • Soluble in water to 100 mM
  • C40H44Cl2N8Ru