(S)-Sulpiride
D2-like dopamine antagonist. Active enantiomer.Product Code: Asc-579 |
Purity: >99% |
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| Buy (S)-Sulpiride from Abcam | ||||
Biological DescriptionSelective D2-like dopamine antagonist (Ki values are ~ 0.015, ~ 0.013, and 1 μM at D2, D3, and D4 receptors respectively). Active enantiomer of Sulpiride (Asc-578). Antipsychotic and prokinetic agent. |
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Useful References | |
The effects of S(-) and R(+) sulpiride, metoclopramide, cisapride and domperidone on the small intestine suggest DA2-receptors are involved in the control of small intestinal transit time in rats. abstract Distinct effects of pramipexole on the proliferation of adult mouse sub-ventricular zone-derived cells and the appearance of a neuronal phenotype. abstract R(+)-8-OH-DPAT, a serotonin(1A) receptor agonist, potentiated S(-)-sulpiride-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens but not striatum. abstract | |
Chemical Information(S)-(-)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide | |
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